Innovation
R&D Breakthrough
Amorphical has recognized the wide and unusual medical potential of ACC, and succeeded in making it suitable for human use after years of research and development.
Currently, we are marketing the DENSITY brand as an advantageous nutrient supplement, which has already become highly popular and includes 3 ACC-based dietary supplements: DENSITY CAPLETS, DENSITY SPORT and DENSITY KIDS. In addition, we are preparing to enter the pharmaceutics market, conducting multiple preclinical and clinical studies on a number of medical conditions, such as hypocalcemia, osteoporosis, fractures, hypoparathyroidism, cancer, inflammatory diseases, and more.
ACC uniqueness
Amorphical has recognized the wide and unusual medical potential of ACC, and successfully made it suitable for human consumption after years of research and development.
Clinical and preclinical trials demonstrated that the absorption of ACC is at least twice faster (on average) than crystalline calcium carbonate and significantly better than calcium citrate (which are the two main active ingredients in commercially available calcium supplements). The calcium supplied by ACC was found to have a significantly higher bioavailability and bioactivity than other available calcium supplement, including unprecedented functionalities.
Research indicates that ACC’s superior absorption and bioactivity help prevent osteoporosis and stimulate bone formation and regeneration, and potentially may treat inflammations by regulating local pH levels.
Amorphical develops the amorphous dietary supplements, branded as DENSITY®, which are already gaining great popularity and success. In addition, we actively research and develop products for entering the medical market of osteoporosis, cancer, hypoparathyroidism and other severe diseases.
Patents
Amorphical has filed 123 patent applications: 55 patents were already allowed in different countries and 68 are in various examination stages registration process, worldwide.
The main patent families, designated for treating various medical conditions, cover:
- Treatment of Cancer, Pain, Neurological Disorders, Alzheimer’s Disease and Dementia
- Osteoporosis, Osteopenia, Hypocalcemia and Hypoparathyroidism
- Muscular Dystrophy, IVF and Sperm Quality
- Muscle Inflammations and Bone Injuries, caused by Repetitive Stress
Osteoporosis & Calcium
Bone loss is a natural process that accelerates over the age of 40 and may cause osteoporosis, fractures and other health issues. The prevalence of osteoporosis has been significantly rising and will further expand according to the International Osteoporosis Foundation, due to the worldwide aging of the population and ever-changing lifestyle habits. Simultaneously, there is a rise in both the prevalence and incidence of related fragility fractures. Globally, it is estimated that 1 in 3 women and 1 in 5 men over the age of 50 will experience osteoporosis fractures. It is assessed that the worldwide number of patients with osteoporotic hip fractures is more than 200 million. In both Europe and the United States, 30% of all women are osteoporotic, and it is estimated that 40% post-menopausal women and 30% men will experience an osteoporotic fracture.
Aside its essential role in healthy bones and teeth, calcium is critical for numerous other physiological processes and body systems – cardiovascular, neurological, etc. Calcium deficiency is not immediately noticeable and typically is not detected by routine blood tests. As necessary, our body maintains the required blood’s calcium levels by decomposing bone tissues, which may cause severe and potentially life-threatening health problems.
Commercially available calcium supplements are not efficient enough for achieving appropriate absorption and utilization of calcium. Our body’s ability to absorb the calcium from those products is limited and depends on the supplement’s ability to break down into calcium ions in our stomach, which are then absorbed into the blood through the intestine’s mucous membrane.